Anti-CDK4 Polyclonal Antibody
應(yīng)用 IHC
稀釋比例IHC 1:50-200.
交叉反應(yīng)Human

產(chǎn)品型號：K106719P

更新時間：2022-08-15

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Anti-CDK4 Polyclonal Antibody

英文名稱	Anti-CDK4 Polyclonal Antibody
宿主	Rabbit
別名	CDK4;Cell division protein kinase 4;CMM3;cyclin dependent kinase 4;PSK J3
應(yīng)用	IHC
稀釋比例	IHC 1:50-200.
交叉反應(yīng)	Human
蛋白分子量	34kDa
Gene ID	1019
保存	Store at -20°C. Avoid freeze / thaw cycles.
儲存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法	Affinity purification
亞型	IgG
免疫原	Recombinant protein of human CDK4
性狀	液體
Public Immunogen Range	Recombinant protein of human CDK4
Subcellular Locations	Cytoplasm Nucleus
Swiss Prot	P11802
克隆類型	Polyclonal Antibody
背景資料	The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers.